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Actiflex

This combination tablet contains Diclofenac Potassium and Paracetamol (also known as Acetaminophen), two active ingredients that work together to relieve pain and inflammation.

  • Diclofenac Potassium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation, pain, and fever by inhibiting cyclooxygenase (COX) enzymes involved in the production of prostaglandins, which mediate pain and inflammation.
  • Paracetamol (Acetaminophen) is an analgesic (pain reliever) and antipyretic (fever reducer) that works by inhibiting a different pathway in the brain that helps control pain and temperature.
  • Recommended Usage
Indications

This combination tablet is typically used for the relief of mild to moderate pain associated with:

  • Musculoskeletal pain (e.g., back pain, muscle aches)
  • Osteoarthritis or rheumatoid arthritis pain
  • Headaches and migraines
  • Dysmenorrhea (menstrual cramps)
  • Post-surgical or post-injury pain
  • Fever and general pain relief (e.g., from colds or flu)
Dosage and Administration

Typical Dosage: The usual dosage is 1 tablet (50 mg Diclofenac Potassium + 325 mg Paracetamol) every 4-6 hours as needed for pain relief.

o Do not exceed 3 tablets in 24 hours unless directed otherwise by a healthcare provider.

Instructions

o Take the tablet orally with a full glass of water.

o It is best to take this medication with food or after meals to reduce stomach irritation from Diclofenac.

o Avoid taking the tablet on an empty stomach if you have a sensitive stomach.

Duration: The treatment duration should be short-term, typically used for a few days to manage acute pain.

Precautions

Liver & Kidney Function: Paracetamol and Diclofenac can affect liver and kidney function. People with liver or kidney disease should use this medication with caution, and regular monitoring may be required.

Gastrointestinal Risk: Diclofenac, as an NSAID, can cause gastrointestinal irritation, ulcers, or bleeding. It should be used with caution in individuals with a history of stomach ulcers or gastrointestinal bleeding.

Cardiovascular Risk: Prolonged use of NSAIDs like Diclofenac may increase the risk of heart attacks or stroke. This is particularly important for people with existing heart disease or hypertension.

Pregnancy & Breastfeeding: This medication should be avoided during the third trimester of pregnancy as it may harm the unborn baby. Use with caution during the first and second trimesters, and consult a doctor before use if pregnant or breastfeeding.

Alcohol: Avoid excessive alcohol consumption while using this medication, as it may increase the risk of liver damage (especially with Paracetamol).

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