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Alprazolam 0.5mg Sustained Release Tablet

Alprazolam is a benzodiazepine that works by enhancing the action of GABA, a neurotransmitter in the brain that has calming effects on the central nervous system.

The sustained-release (SR) formulation allows for a longer duration of action compared to immediate-release forms, providing a more consistent therapeutic effect throughout the day.

  • Recommended Usage
Indications
  • Generalized Anxiety Disorder (GAD)
  • Panic Disorder (with or without agoraphobia)
  • Short-term relief of severe anxiety symptoms
Dosage

Typical Starting Dose: 0.5 mg once daily, with the possibility of titration based on individual needs and response.

Dosage Adjustments: Depending on the response, the dose may be gradually increased, typically up to 1 mg–3 mg daily, divided into 1–2 doses.

Administration: Take with or without food, swallowing the tablet whole. Do not crush or chew.

Precautions

Dependence and Withdrawal: Long-term use may lead to dependence, and gradual tapering is recommended if discontinuing to avoid withdrawal symptoms.

CNS Effects: May cause drowsiness, dizziness, or impaired coordination. Use caution when performing tasks requiring full alertness.

Elderly and Debilitated Patients: Start with lower doses due to increased sensitivity to the drug.

Drug Interactions: May interact with other CNS depressants (e.g., alcohol, opioids) and other medications that affect the liver.

Pregnancy: Generally avoided during pregnancy, especially in the first trimester.

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