Indication
- Autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus)
- Inflammatory conditions (e.g., inflammatory bowel disease, dermatitis)
- Allergic reactions (e.g., severe allergic responses, asthma exacerbations)
- Musculoskeletal disorders (e.g., Duchenne muscular dystrophy)
- Adrenal insufficiency (e.g., Addison’s disease)
Dosage and Administration
Route of Administration: Oral tablet.
Typical dose for adults and children: 6 mg once daily or as directed by a healthcare provider, based on the specific condition being treated.
For chronic conditions: Dosage adjustments or tapering may be necessary, especially for long-term therapy.
Tapering: Gradual tapering of the dose is required to avoid withdrawal symptoms during prolonged use.
Precautions
Avoid use in patients with known hypersensitivity to deflazacort or any component of the tablet.
Use cautiously in patients with a history of gastrointestinal ulcers, infections, or psychiatric disorders (e.g., depression).
Long-term use may cause side effects such as osteoporosis, hypertension, weight gain, or diabetes.
Not recommended during pregnancy or breastfeeding unless deemed necessary by a healthcare provider.
Contraindications
Hypersensitivity to deflazacort or any excipient in the tablet.
Active untreated infections (e.g., fungal or bacterial infections).
Severe liver impairment.
Key Benefits
Anti-Inflammatory Action: Reduces inflammation effectively in conditions such as arthritis, asthma, and autoimmune disorders.
Immunosuppressive Effect: Helps control autoimmune diseases by modulating the immune response.
Well-Tolerated: Deflazacort is associated with fewer side effects than other corticosteroids, particularly related to fluid retention and weight gain.
Convenient Dosage: The 6 mg tablet provides flexibility in dosing, particularly for patients requiring lower doses or fine-tuning of their treatment regimen.
Improved Quality of Life: Manages chronic inflammatory and autoimmune conditions, enhancing comfort and functional ability in daily life.