Cerofi-200
Cefixime is a third-generation cephalosporin antibiotic that works by inhibiting the bacterial cell wall synthesis, leading to bacterial cell death. The 200 mg dispersible tablet formulation of cefixime is commonly used for treating bacterial infections in both children and adults, especially for those who may have difficulty swallowing standard tablets. This tablet can be easily dissolved in water, making it easier to ingest, particularly for pediatric patients.
- Recommended Usage
Indications
- Respiratory Tract Infections: Including sinusitis, pharyngitis, and tonsillitis Such as bronchitis and pneumonia.
- Urinary Tract Infections: Cystitis and pyelonephritis.
- Skin and Soft Tissue Infections: Infections such as cellulitis and wound infections caused by susceptible organisms.
- Ear Infections: Otitis media.
- Gastrointestinal Infections: Enteritis caused by susceptible organisms.
Dosage and Administration
Standard Dosage: 1 tablet (200 mg) once daily, or 100 mg twice daily, depending on the infection type and severity.
Children (6 months to 12 years): The dose is usually 8 mg/kg/day, divided into one or two doses. The exact dose depends on the child’s weight and the infection being treated.
For patients with renal dysfunction, dose adjustments may be required. Cefixime is primarily excreted via the kidneys, so the dosage should be carefully adjusted based on the degree of renal impairment.
Precautions
Patients with a known allergy to cephalosporins or penicillins should not take cefixime, as there is a possibility of cross-reactivity.
In patients with renal impairment, the dose of Cefixime should be adjusted as it is excreted by the kidneys. Renal function should be monitored, and dose modifications should be considered in patients with moderate to severe kidney dysfunction.
Cefixime may disrupt the normal flora of the intestines, leading to diarrhea or more serious conditions like Clostridium difficile-associated diarrhea.
Prolonged use of cefixime may lead to the overgrowth of non-susceptible organisms, including fungi or resistant bacteria. If a secondary infection develops, treatment with appropriate antibiotics should be initiated.
Benefits
Broad-Spectrum Activity: Effective against a wide range of gram-positive and gram-negative bacteria, treating respiratory, urinary tract, and ear infections, as well as tonsillitis and bronchitis.
Effective for Common Infections: Commonly used for infections like acute otitis media (ear infections), sinusitis, pharyngitis, and cystitis (bladder infections).
Minimal Side Effects: Generally well-tolerated with mild side effects like diarrhea or nausea.
Convenient Dosage: Offers a single-dose, effective treatment for many bacterial infections, making it a convenient choice for patients needing quick relief.
