CLOZIP-SL is a topical lotion that combines clobetasol propionate, a potent corticosteroid, with salicylic acid (3%), a keratolytic agent. This formulation is designed to treat inflammatory skin conditions, particularly those involving thickened skin or scaling, such as psoriasis and seborrheic dermatitis, while providing easier application to areas that may be difficult to treat with creams or ointments (e.g., scalp, hairy areas).
Route of Administration: Topical application.
Typical dose for adults and children: Apply a small amount to the affected area 1-2 times daily, or as directed by a healthcare provider.
Duration of treatment: Generally used for short-term periods (typically no more than 2 consecutive weeks) unless directed otherwise by a healthcare provider.
Application: Apply the lotion in a thin layer to the affected area and rub in gently.
Avoid use in patients with known hypersensitivity to clobetasol propionate, salicylic acid, or any component of the lotion.
Caution for sensitive areas: Use with caution on the face, groin, or armpits, as the skin is thinner in these areas.
Do not apply to broken, infected, or raw skin unless directed by a healthcare provider.
Prolonged use of corticosteroids like clobetasol can lead to side effects such as skin thinning, delayed wound healing, or systemic absorption.
Salicylic acid caution: Excessive use or application over large areas may cause irritation or systemic absorption, particularly in patients with sensitive skin or children.
Discontinue use if irritation, allergic reactions, or signs of excessive dryness occur.
Hypersensitivity to clobetasol propionate, salicylic acid, or any excipients in the lotion.
Active untreated infections (e.g., fungal, bacterial, or viral) unless prescribed by a healthcare provider.
Not recommended for use on open wounds or raw skin unless specifically advised.
Salicylic acid caution: Avoid use in patients with known salicylate sensitivity or toxicity.
Dual Action: Combines clobetasol propionate (corticosteroid) for inflammation reduction with salicylic acid (keratolytic) to soften and remove thickened skin, improving treatment efficacy.
Effective for Scalp and Hairy Areas: The lotion formulation is easier to apply to areas with hair or other hard-to-reach areas where creams or ointments may not be practical.
Reduces Inflammation and Scaling: Clobetasol reduces inflammation, while salicylic acid helps exfoliate and smooth the skin, providing relief from thick, scaly plaques.
Promotes Skin Recovery: The combination of anti-inflammatory and exfoliating properties allows for faster healing of chronic inflammatory skin conditions.
Improved Skin Texture: The lotion helps improve skin appearance by removing excess buildup and promoting smoother skin.