Divalproex Sodium E.R. 250mg Tablet
• Divalproex Sodium E.R. is the extended-release form of valproic acid, a medication used to treat seizures, bipolar disorder, and to prevent migraines.
• The extended-release formulation provides steady drug levels over a longer period, typically requiring once-daily dosing.
- Recommended Usage
Indications
- Epilepsy: To control seizures, including generalized tonic-clonic seizures, absence seizures, and partial seizures.
- Bipolar Disorder: For the treatment of mania associated with bipolar disorder.
- Migraine Prophylaxis: To prevent migraines.
Dosage and Administration
Typical Starting Dose: 250 mg once daily.
Dosage Adjustment: Dose may be gradually increased based on clinical response, up to 1000 mg/day for epilepsy and bipolar disorder.
Administration: Take once daily with or without food. Do not chew or crush the tablet.
Precautions
Liver Function: Monitor for liver toxicity and pancreatitis (inflammation of the pancreas), especially during the first 6 months.
Pregnancy: Can cause birth defects; use only if necessary and after careful consultation with a healthcare provider.
Blood Disorders: Regular monitoring of blood counts (platelets, white blood cells) is needed.
CNS Effects: Can cause sedation, drowsiness, or cognitive impairment.
