Indication
- Systemic fungal infections such as:
o Aspergillosis (fungal infection caused by Aspergillus species)
o Histoplasmosis (lung infection caused by the Histoplasma fungus)
o Blastomycosis (a fungal infection that affects the lungs and skin)
o Candidiasis (Candida infections, including in the bloodstream)
o Onychomycosis (fungal infections of the nails)
- Fungal skin infections that require systemic treatment.
Dosage and Administration
Typical Dosage: The usual dose for most fungal infections is 100 mg once or twice daily, depending on the type and severity of the infection.
Instructions: Take the capsules with food to increase absorption and minimize stomach upset.
Duration: Treatment duration can range from several weeks to several months, depending on the type and severity of the infection.
Precautions
Liver Disease: Itraconazole can affect liver function, so it should be used with caution in patients with liver problems. Regular liver function monitoring may be necessary.
Heart Conditions: Use with caution in patients with heart conditions, as itraconazole can cause changes in heart rhythm.
Pregnancy: Not recommended during pregnancy unless absolutely necessary, as it can be harmful to the fetus.
Drug Interactions: Itraconazole can interact with several medications (e.g., warfarin, benzodiazepines), so it's essential to inform your doctor of all other medications you're taking.
Side Effects: Possible side effects include nausea, headache, dizziness, liver problems, and skin reactions. Seek medical advice if you experience any severe side effects like yellowing of the skin or eyes, or unusual bruising.