Toyclav-625
Amoxicillin (500 mg) and Clavulanate (125 mg) is a combination antibiotic used to treat a variety of bacterial infections. Clavulanate helps enhance the efficacy of Amoxicillin by inhibiting beta-lactamase enzymes that some bacteria produce to resist the effects of Amoxicillin.
- Recommended Usage
Indications
- Respiratory infections : sinusitis, bronchitis.
- Ear infections : otitis media
- Urinary tract infections : cystitis
- Skin infections : cellulitis
- Dental infections and bite wounds
Dosage and Administration
500 mg of Amoxicillin and 125 mg of Clavulanate every 12 hours for mild to moderate infections.
For more severe infections, the dosage may be increased to 875 mg of Amoxicillin and 125 mg of Clavulanate every 12 hours.
Pediatric: Adjusted based on weight and the infection, 25-45 mg/kg/day, divided into two doses every 12 hours.
Precautions
Allergic reactions to penicillin or other beta-lactam antibiotics.
Use with caution in patients with liver or kidney disease.
May cause gastrointestinal disturbances (e.g., diarrhea, nausea, vomiting).
Prolonged use can lead to superinfections (e.g., Clostridium difficile-associated diarrhea).
Pregnancy: Generally safe (Category B), but consult a doctor before use.
Benefits
Broad-spectrum antibiotic activity against a variety of gram-positive and gram-negative bacteria, including those resistant to amoxicillin alone.
Clavulanate enhances effectiveness by preventing bacterial beta-lactamases from breaking down Amoxicillin.
Tablet form is convenient for adults and children who can swallow tablets.
