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Amoxicillin is a penicillin-type antibiotic that is used to treat a variety of bacterial infections. It works by preventing bacteria from forming their cell wall, which ultimately leads to their death. Clavulanate, also known as clavulanic acid, is a beta-lactamase inhibitor that helps prevent bacteria from breaking down amoxicillin, thus enhancing the effectiveness of amoxicillin in treating bacterial infections that would otherwise be resistant. This combination product is often used for treating infections caused by bacteria that are resistant to amoxicillin alone.

  • Recommended Usage
Indications
  • Respiratory infections : sinusitis, bronchitis.
  • Ear infections : otitis media
  • Urinary tract infections : cystitis
  • Skin infections : cellulitis
  • Dental infections and bite wounds
Dosage and Administration

Adults: 250-500 mg every 12 hours, depending on infection severity.

Pediatric: 25-45 mg/kg/day in divided doses every 12 hours (based on the infection)

Precautions
  • Allergy to penicillin or beta-lactam antibiotics.
  • Liver or kidney conditions may require dose adjustments.
  • Gastrointestinal side effects (e.g., diarrhea, nausea).
  • Monitor for allergic reactions or signs of liver damage.
  • Pregnancy: Generally safe (Category B), consult a doctor.
  • Benefits

    The combination of amoxicillin and clavulanate is effective against a broad range of gram-positive and gram-negative bacteria, as well as beta-lactamase-producing organisms that are resistant to amoxicillin alone.

    Clavulanate helps protect amoxicillin from being broken down by bacterial enzymes (beta-lactamases), making this combination especially useful for treating infections caused by resistant bacteria.

    The dry suspension format is easy for children or individuals who may have difficulty swallowing tablets.

    Used widely to treat infections of the ear, throat, respiratory tract, urinary tract, and skin, this combination is a well-established treatment option for several common infections.

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