Griseofulvin 500 mg micronised tablets are an oral antifungal medication used to treat dermatophyte infections (fungal infections affecting the skin, hair, and nails). The micronised form of griseofulvin has smaller particle size, which increases its absorption in the body, making it more effective compared to non-micronised forms.
Griseofulvin is primarily used to treat superficial fungal infections caused by dermatophytes, such as:
Usual Dosage:
o For adults: 500 mg once daily or 250 mg twice daily, depending on the severity of the infection.
o For children: The dosage depends on body weight and the type of infection. Typically, 10-20 mg/kg body weight per day.
Instructions:
o Take the tablet with a fatty meal or milk to increase absorption.
o Swallow the tablet whole with a glass of water. Do not chew or crush the tablet.
Duration:
o Treatment duration can range from 2 to 6 weeks for skin infections.
o For nail infections or scalp infections, treatment might last several months (up to 6 months for nail infections).
Liver Disease: Griseofulvin should be used cautiously in patients with liver disorders as it can affect liver function. Liver function tests may be necessary during treatment.
Pregnancy: Griseofulvin is contraindicated during pregnancy due to potential risks to the fetus. Women should avoid pregnancy during treatment and for at least one month after completing therapy.
Alcohol: Avoid excessive alcohol consumption, as it may increase the risk of liver toxicity.
Drug Interactions: Griseofulvin can interact with several medications, such as warfarin, oral contraceptives, and barbiturates. Always inform your doctor about any other medications you're taking.
Side Effects: Common side effects include headache, gastrointestinal issues (nausea, diarrhea), and dizziness. Rare side effects include liver toxicity, allergic reactions, and skin rashes.