Prasugrel
Prasugrel is an antiplatelet medication used to prevent blood clots in people with acute coronary syndrome (ACS) or those undergoing percutaneous coronary intervention (PCI) (e.g., stent placement). It works by blocking the P2Y12 receptor on platelets, preventing them from clumping together and forming clots.
- Recommended Usage
Indications:
- Acute coronary syndrome (ACS): Used in patients with NSTEMI or STEMI undergoing PCI.
- Preventing stent thrombosis: Reduces the risk of clots forming in stents post-procedure.
Dosage:
- Loading dose: 60 mg once.
- Maintenance dose: 10 mg once daily (5 mg if the patient is older than 75 or weighs less than 60 kg).
Precautions:
- Bleeding risk: Increases the risk of bleeding, especially in those with a history of stroke, active bleeding, or undergoing surgery.
- Age and weight considerations: Lower dose (5 mg) for those over 75 or weighing less than 60 kg.
- Contraindications: History of stroke/TIA, active bleeding, or hypersensitivity.
Key Benefits:
- Reduces the risk of clot formation in patients with ACS or after stent placement.
- Often used with aspirin in dual antiplatelet therapy (DAPT) for better results.
Key Benefits:
- Reduces the risk of clot formation in patients with ACS or after stent placement.
- Often used with aspirin in dual antiplatelet therapy (DAPT) for better results.
Side Effects:
Monitoring:
Prasugrel is highly effective in reducing cardiovascular events but requires careful management due to the increased risk of bleeding.
